Epilepsy control with carbamazepine monotherapy from a genetic perspective
نویسندگان
چکیده
Ethnicity variation is one of the main factors that may affect drug response in clinical practice. As MTHFR gene affects different transcriptome and proteome which drugs. Purpose current study was to observe possible variations plasma levels carbamazepine monotherapy seizures' control Pakhtun population Khyber Pakhtunkhwa (KP) context (C677T A1298C) polymorphisms.
منابع مشابه
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متن کاملLevetiracetam monotherapy—Outcomes from an epilepsy clinic
INTRODUCTION Levetiracetam (LEV) is a broad spectrum antiepileptic drug (AED) with a unique mechanism of action. This retrospective audit explores outcomes in patients commenced on LEV monotherapy at the Epilepsy Unit at the Western Infirmary, Glasgow, Scotland from 1st January 2001 until 30th June 2009. METHODS LEV monotherapy was started in 228 patients (89 men, 139 women, aged 12-81 years ...
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ژورنال
عنوان ژورنال: Journal of the Neurological Sciences
سال: 2021
ISSN: ['0022-510X', '1878-5883']
DOI: https://doi.org/10.1016/j.jns.2021.119182